1. Contact address(Person who provides information. This information will be treated confidentially)?

Title: MD

First Name: Fernando

Last Name: Ramirez

State: Tijuana

Country: Mexico

Institution: International Spinal Cord Regeneration Center

Telephone: 619/463-5350

Email: www.electriciti.com/spinal/

2. What is the source of your information about human xenotransplantation practices?

http://www.healingtherapies.info/shark_embryo_cell_transplantation.html

3. What is the therapeutic purpose of this xenotransplantation treatment?

Spinal Cord injury

4. Where and when is this human xenotransplantation practice taking place?

Country: Mexico

Timing: In the early 1990’s

5. Is this treatment part of a clinical trial?

Yes

6. How many patients are included in this clinical trial?

30

7. What are the inclusion criteria for patient selection?

i. Duration on the waiting list? Unknown

ii. Life-threatening diseases without alternative therapy? No

iii. Is a protocol available? No

8. What is the animal source of the xenotransplantation product?

Blue shark

9.Source Animals
Do you have information about source animals?

No

10. Testing of safety
Do you have information about testing of safety?

No

11. What type of cells/tissues/organs was transplanted?

Cells: Embryonic stem cells

Tissues:

Organs:

Others:

12.What type of exposure to xenogeneic cells was involved?

• Solid-organ Xenotransplantation: No
• Cellular Xenotransplantation: Yes
• Tissue Xenotransplantation: No
• Human cells exposed to xenogeneic Feeder cells: No
• Extracorporeal perfusion: No
• Encapsulation: No
• Other bioartificial isolation device:
• Others:

13. Transplant
Do you have information about transplant recipients?

No

14. Have results been presented at a scientific congress?

Unknown

if yes, where?

15. Have results been published in a scientific journal?

Unknown

if yes, Where?

16. Is this human clinical trial performed with governmental and/or institutional oversight and supervision?

Unknown

If yes, which?

17. Comment