1. Contact address(Person who provides information. This information will be treated confidentially)?

Title: Mr.

First Name: Grant

Last Name: Andrea

State:

Country: New Zealand

Institution: LCT

Telephone: +64 9 270 7941

Email: agrant@lctglobal.com

2. What is the source of your information about human xenotransplantation practices?

Congress

3. What is the therapeutic purpose of this xenotransplantation treatment?

Parkinson disease

4. Where and when is this human xenotransplantation practice taking place?

Country: New Zealand

Timing: In progress

5. Is this treatment part of a clinical trial?

Yes

6. How many patients are included in this clinical trial?

4

7. What are the inclusion criteria for patient selection?

i. Duration on the waiting list?

ii. Life-threatening diseases without alternative therapy? No

iii. Is a protocol available? No

8. What is the animal source of the xenotransplantation product?

Pig

9.Source Animals

Do you have information about source animals?

No

10. Testing of safety

Do you have information about testing of safety?

No

11. What type of cells/tissues/organs was transplanted?

Cells:

Tissues:

Organs:

Others: Choroid / Plexus

12.What type of exposure to xenogeneic cells was involved?

• Solid-organ Xenotransplantation: No
• Cellular Xenotransplantation: Yes
• Tissue Xenotransplantation: No
• Human cells exposed to xenogeneic Feeder cells: No
• Extracorporeal perfusion: No
• Encapsulation: No
• Other bioartificial isolation device:
• Others:

13. Do you have information about transplant recipients?

No

14. Have results been published in a scientific congress?

Yes

if yes, where?

The joint congress of IXA and organ transplantation in ABO-incompatible and hyperimmunized recipient, 2013, Osaka, Japan

15. Have results been published in a scientific journal?

No

if yes, Where?

16. Is this human clinical trial performed with governmental and/or institutional oversight and supervision?

No

If yes, which?

17. Comment

Internet: http:// www.lctglobal.com/html/blob.php/1280877.pdf?attach=0&documentCode=5188&elementId=20084